{"id":46,"date":"2021-02-04T13:55:45","date_gmt":"2021-02-04T13:55:45","guid":{"rendered":"http:\/\/riedellab.org\/wordpress\/?page_id=46"},"modified":"2025-07-23T22:32:43","modified_gmt":"2025-07-23T20:32:43","slug":"publications","status":"publish","type":"page","link":"http:\/\/riedellab.org\/wordpress\/?page_id=46","title":{"rendered":"Publications"},"content":{"rendered":"\n

Kavsek, A., Salignon, J., Millan-Ari\u00f1o, L, Marcinkowski, P., Sen, I., Riedel, C.G.<\/strong> (2025) LIN-39 is a neuron-specific developmental determinant of longevity in Caenorhabditis elegans<\/em> with reduced insulin signaling. Nature Communications<\/strong> 16(1):6566.<\/p>\n\n\n\n

Breusegem, S.Y., Houghton. J., Romero-Bueno, R., Fragoso-Luna, A., Kentistou, K.A., Ong, K.K., Janssen, A.F.J., Bright, N.A., Riedel, C.G.<\/strong>, Perry, J.R.B., Askjaer, P., Larrieu, D. (2025) A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein translation. Nature Communications<\/strong> 16(1):1681.<\/p>\n\n\n\n

Romero-Bueno, R., Fragoso-Luna, A., Ayuso, C., Mellmann, N., Kavsek, A., Riedel, C.G.<\/strong>, Ward, J.D., Askjaer, P. (2024) A progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans<\/em>. EMBO Journal<\/strong> 43, 5718\u20135746.<\/p>\n\n\n\n

Salignon, J.*, Millan-Ari\u00f1o<\/strong>, L., Garcia, M., Riedel, C.G.<\/strong>* (2024) Cactus: a user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis. Genomics<\/strong> 116(4):110858. (*: equal correspondence)<\/p>\n\n\n\n

Emerson, F.J., Chiu, C., Lin, L.Y., Riedel, C.G.<\/strong>, Zhu, M., Lee, S.S. (2024) The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans. <\/em>Nature Communications <\/strong>14;15(1):2320.<\/p>\n\n\n\n

Coschiera, A., Yoshihara, M., Lauter, G., Ezer, S., Pucci, M., Li, H., Kav\u0161ek, A.<\/strong>, Riedel, C.G.<\/strong>, Kere, J., Swoboda, P. (2024) Primary cilia promote the differentiation of human neurons through the WNT signaling pathway. BMC Biology<\/strong> 22, 48<\/p>\n\n\n\n

Annunziata, C., Castoldi, F., Schlegel, J., Ang, H.X.<\/strong>, Ristovska, M., Melini, S., Welch, R., Riedel, C.G.<\/strong>, Pietrocola, F. (2023) A versatile method for the identification of senolytic compounds. Cell Stress<\/strong> 7: 105.<\/p>\n\n\n\n

Caron, M., Robert, V., Gely, L., Adrait, A., Pakulska, V., Cout\u00e9, Y., Chevalier, M.<\/strong>, Riedel, C.G.<\/strong>, Bedet, C., Palladino, F. (2023) SIN3 acts in distinct complexes to regulate the germline transcriptional program in C. elegans<\/em>. Development<\/strong> 150:dev201755.<\/p>\n\n\n\n

Salignon, J.<\/strong>, Faridani, O., Miliotis, T., Janssens, G.E.<\/strong>, Chen, P., Zarrouki, B., Sandberg, R., Davidsson, P., Riedel, C.G. <\/strong>(2023) <\/strong>Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis. Aging<\/strong> 15.<\/p>\n\n\n\n

Salignon, J.<\/strong>, Rizzuto, D., Calder\u00f3n-Larra\u00f1aga, A., Zucchelli, A., Fratiglioni, L., Riedel, C.G.*<\/strong>, Vetrano, D.L.* (2023) Beyond chronological age: a multidimensional approach to survival prediction in older adults. The Journals of Gerontology: Series A, Biological Sciences and Medical Sciences <\/strong>78(1):158-166. (*: equal correspondence)<\/p>\n\n\n\n

Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J.A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B.H., Ermolaeva, M., Ewald, C.Y., Ferrucci, L., Florian, M.C., Fortney, K., Freund, A., Georgievskaya, A., Gladyshev, V.N., Glass, D., Golato, T., Gorbunova, V., Hoejimakers, J., Houtkooper, R.H., Jager, S., Jaksch, F., Janssens, G., Jensen, M.B., Kaeberlein, M., Karsenty, G., Keizer, P. de, Kennedy, B., Kirkland, J.L., Kjaer, M., Kroemer, G., Lee, K.-F., Lemaitre, J.-M., Liaskos, D., Longo, V.D., Lu, Y.-X., MacArthur, M.R., Maier, A.B., Manakanatas, C., Mitchell, S.J., Moskalev, A., Niedernhofer, L., Ozerov, I., Partridge, L., Passegu\u00e9, E., Petr, M.A., Peyer, J., Radenkovic, D., Rando, T.A., Rattan, S., Riedel, C.G.<\/strong>, Rudolph, L., Ai, R., Serrano, M., Schumacher, B., Sinclair, D.A., Smith, R., Suh, Y., Taub, P., Trapp, A., Trendelenburg, A.-U., Valenzano, D.R., Verburgh, K., Verdin, E., Vijg, J., Westendorp, R.G.J., Zonari, A., Bakula, D., Zhavoronkov, A., Scheibye-Knudsen, M. (2022<\/strong>) Meeting Report: Aging Research and Drug Discovery. Aging <\/strong>14.<\/p>\n\n\n\n

Casteels, T., Zhang, Y., Frogne, T., Sturtzel, C., Lardeau, C.H., Sen, I., Liu, X., Hong, S., Pauler, F.M., Penz, T., Brandstetter, M., Barbieux, C., Berishvili, E., Heuser, T., Bock, C., Riedel, C.G.<\/strong>, Meyer, D., Distel, M., Hecksher-S\u00f8rensen, J., Li, J., Kubicek, S. (2021)<\/strong> An inhibitor-mediated beta cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation. Molecular Metabolism<\/strong> 101329.<\/p>\n\n\n\n

Sen, I., Kav\u0161ek, A., Riedel, C.G. (2021) <\/strong>Chromatin Immunoprecipitation and Sequencing (ChIP\u2010seq) Optimized for Application in Caenorhabditis elegans<\/em>. Current Protocols<\/strong> 1(1): e187.<\/p>\n\n\n\n

Mkrtchyan, G., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., de Cabo, R., Campisi, J., Cuervo, A.M., Demaria, M., Ewald, C.Y., Fei Fang, E., Faragher, R., Ferrucci, L., Freund, A., Silva-Garc\u00eda, C.G., Georgievskaya, A., Gladyshev, V.N., Glass, D.J., Gorbunova, V., de Grey, A., He, W.W., Hoeijmakers, J., Hoffmann, E.R., Horvath, S., Houtkooper, R.H., Jensen, M.K., Borch Jensen, M., Kane, A., Kassem, M., de Keizer, P., Kennedy, B., Karsenty, G., Lamming, D.W., Lee, K.F., MacAulay, N., Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, A., Niedernhofer, L., Osborne, B., Pak, H.H., Parkhitko, A., Raimundo, N., Rando, T.A., Juel Rasmussen, L., Reis, C., Riedel, C.G.,<\/strong> Franco-Romero, A., Schumacher, B., Sinclair, D.A., Suh, Y., Taub, P.R., Toiber, D., Treebak, J.T., Valenzano, D.R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, D., Zhavoronkov, A., Scheibye-Knudsen, M. (2021<\/strong>) ARDD 2020: from aging mechanisms to interventions. Aging<\/strong> 12(24): 24484-24503. <\/p>\n\n\n\n

Millan-Arino, L.,<\/strong> Yuan, Z.F., Oomen, M.E.<\/strong>, Brandenburg,<\/strong> S., Chernobrovkin, A., Salignon, J.<\/strong>, K\u00f6rner, L.,<\/strong> Zubarev, R.A., Garcia, B.A., Riedel, C.G.<\/strong> (2020<\/strong>) Histone purification combined with high-resolution mass spectrometry to examine histone posttranslational modifications and histone variants in Caenorhabditis elegans<\/em>. Current Protocols in Protein Science<\/strong> 102(1): e114.<\/em><\/p>\n\n\n\n

Sen, I., <\/strong>Chernobrovkin, A., Puerta Cavanzo, N., Liu, M., Lin, X.X., Baskaner, B., Brandenburg, S., <\/strong>Zubarev, R.A., Riedel, C.G.<\/strong> (2020<\/strong>) DAF-16\/FOXO requires Protein Phosphatase 4 to initiate the transcription of stress resistance and longevity promoting genes. Nature Communications<\/strong> 11(1): 138.<\/em><\/p>\n\n\n\n

Janssens, G.E., Lin, X.X., Millan-Arino, L., Sen, I., Kavsek, A., <\/strong>Seinstra, R.I., Stroustrup, N., Nollen, E.A.A., Riedel, C.G.<\/strong> (2019<\/strong>) Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging. Cell Reports<\/strong> 27(2): 467-480.<\/p>\n\n\n\n

Lin, X.X., Sen, I., Janssens, G.E., Zhou, X.,<\/strong> Fonslow, B.R., Edgar, D., <\/strong>Stroustrup, N., Swoboda, P., Yates 3rd<\/sup>, J.R., Ruvkun, G., Riedel, C.G.<\/strong> (2018<\/strong>) DAF-16\/FOXO and HLH-30\/TFEB function as combinatorial transcription factors to promote stress resistance and longevity. Nature Communications<\/strong> 9(1): 4400.<\/p>\n\n\n\n

Zhou, X., Sen, I., Lin, X.X, Riedel, C.G.<\/strong> (2018<\/strong>) Regulation of age-related decline by transcription factors and their crosstalk with the epigenome. Current Genomics<\/strong> 19(6): 464-482.<\/p>\n\n\n\n

Lezzerini, M., Riedel, C.G.<\/strong> (2016<\/strong>) ATP-dependent chromatin remodeling: from development to disease. Book Chapter in \u201cChromatin Regulation and Dynamics\u201d, Elsevier<\/strong>, ISBN: 978-0-12-803395-1, 95-116.<\/p>\n\n\n\n

Heimbucher, T., Liu, Z., Bossard, C., McCloskey, R.,Carrano, A., Riedel, C.G.,<\/strong> Tanasa, B., Klammt, C., Fonslow, B.R., Riera, C., Lillemeier, B.F., Kemphues, K., Yates, J.R. 3rd<\/sup>, O’Shea, C., Hunter, T., Dillin, A. (2015<\/strong>) The deubiquitylase MATH-33 controls DAF-16 stability and function in metabolism and longevity. Cell Metabolism<\/strong> 22(1):151-63.<\/p>\n\n\n\n

Riedel, C.G.,<\/strong> Dowen, R.H., Lourenco, G.F., Kirienko, N.V., Heimbucher, T., West, J.A., Bowman, S.K., Kingston, R.E., Dillin, A., Asara, J.M., Ruvkun, G. (2013<\/strong>) DAF-16 employs the chromatin remodeller SWI\/SNF to promote stress resistance and longevity. Nature Cell Biology<\/strong> 15(5): 491-501.<\/p>\n\n\n\n

Zhang, C., Montgomery, T.A., Fischer, S.E., Garcia, S.M., Riedel, C.G.,<\/strong> Fahlgren, N., Sullivan, C.M., Carrington, J.C., Ruvkun, G. (2012<\/strong>) The Caenorhabditis elegans RDE-10\/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Current Biology<\/strong> 22: 881-90.<\/p>\n\n\n\n

Hayes, G.D., Riedel, C.G.,<\/strong> Ruvkun, G. (2011<\/strong>) The Caenorhabditis elegans<\/em> SOMI-1 zinc-finger protein and SWI\/SNF promote regulation of development by the mir-84 microRNA. Genes & Development<\/strong> 25: 2079-2092.<\/p>\n\n\n\n

Rizki, G., Iwata, T.N., Li, J., Riedel, C.G.,<\/strong> Lafontaine Picard, C., Jan, M., Murphy, C.T., Lee, S.S. (2011<\/strong>) The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1\/SIRT1 collaborate to regulate DAF-16\/FOXO. PLoS Genetics<\/strong> 7(9):e1002235.<\/p>\n\n\n\n

Rumpf, C., Cipak, L., Dudas, A., Benko, Z., Pozgajova, M., Riedel, C.G.,<\/strong> Ammerer, G., Mechtler, K., Gregan, J. (2010<\/strong>) Casein kinase 1 is required for efficient removal of Rec8 during meiosis I. Cell Cycle<\/strong> 9(13): 2657-2662.<\/p>\n\n\n\n

Riedel, C.G.<\/strong> (2010<\/strong>) Toward the mechanisms preventing merotelic kinetochore-microtubule attachments. Cell Cycle<\/strong> 9 (20).<\/p>\n\n\n\n

Curran, S.P., Wu, X., Riedel, C.G.,<\/strong> Ruvkun, G. (2009<\/strong>) A soma-to-germline transformation in long-lived Caenorhabditis elegans<\/em> mutants. Nature<\/strong> 459: 1079-1084.<\/p>\n\n\n\n

Gregan, J.*, Riedel, C.G.*, Pidoux, A.L.*,<\/strong> Katou, Y., Rumpf, C., Schleiffer, A., Kearsey, S.E., Shirahige, K., Allshire, R.C., Nasmyth, K. (2007<\/strong>) The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation. Current Biology<\/strong> 17: 1190-1200. (*: equal contrib.)<\/p>\n\n\n\n

Gregan, J., Riedel, C.G., <\/strong>Petronczki, M., Cipak, L., Rumpf, C., Poser, I., Buchholz, F., Mechtler, K., Nasmyth, K. (2007<\/strong>) Tandem affinity purification of functional TAP-tagged proteins from human cells. Nature Protocols<\/strong> 2: 1145-1151.<\/p>\n\n\n\n

Riedel, C.G.*, <\/strong>Katis, V.L.*, Katou, Y., Mori, S., Itoh, T., Helmhart, W., Galova, M., Petronczki, M., Gregan, J., Cetin, B., Mudrak, I., Ogris, E., Mechtler, K., Pelletier, L., Buchholz, F., Shirahige, K., Nasmyth, K. (2006<\/strong>) Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature<\/strong> 441: 53-61. (*: equal contrib.)<\/p>\n\n\n\n

Riedel, C.G.*, <\/strong>Mazza, M.*, Maier, P., Korner, R., Knop, M. (2005<\/strong>) Differential requirement for phospholipase D\/Spo14 and its novel interactor Sma1 for regulation of exocytotic vesicle fusion in yeast meiosis. Journal of Biological Chemistry<\/strong> 280: 37846-37852. (*: equal contrib.)<\/p>\n\n\n\n

Riedel, C.G.*, <\/strong>Gregan, J.*, Gruber, S., Nasmyth, K. (2004<\/strong>) Is chromatin remodeling required to build sister-chromatid cohesion? Trends in Biochemical Sciences<\/strong> 29: 389-392. (*: equal contrib.)<\/p>\n\n\n\n

Knop, M., Barr, F., Riedel, C.G., <\/strong>Heckel, T., Reichel, C. (2002<\/strong>) Improved version of the red fluorescent protein (drFP583\/DsRed\/RFP). Biotechniques<\/strong> 33: 592, 594, 596-598.
<\/p>\n","protected":false},"excerpt":{"rendered":"

Kavsek, A., Salignon, J., Millan-Ari\u00f1o, L, Marcinkowski, P., Sen, I., Riedel, C.G. (2025) LIN-39 is a neuron-specific developmental determinant of<\/p>\n

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